BDBM283431 6-((4-(((6-fluoro-1H-indol-5- yl)methyl)carbamoyl)pyridin-2-yl)methyl)-3- methylquinoline-8-carboxamide::US10023557, Example 83::US10266515, Example 83::US10308637, Example 83::US11021463, Example 83::US9611252, Example 83

SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cc4cc[nH]c4cc3F)cc2c1)C(N)=O

InChI Key InChIKey=UZTOCULVDVRYTA-UHFFFAOYSA-N

Data  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283431   

TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283431(6-((4-(((6-fluoro-1H-indol-5- yl)methyl)carbamoyl)...)
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent