BDBM283709 N-[4-(azetidin-3-yloxy)phenyl]-4-chloro-3-(4-chlorophenyl)-1H-pyrazole-5-carboxamide::US10023559, Example 34

SMILES Clc1c(n[nH]c1C(=O)Nc1ccc(OC2CNC2)cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=ZDNQYRXMTQQWCD-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283709   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM283709(N-[4-(azetidin-3-yloxy)phenyl]-4-chloro-3-(4-chlor...)
Affinity DataKi:  2.10nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM283709(N-[4-(azetidin-3-yloxy)phenyl]-4-chloro-3-(4-chlor...)
Affinity DatapH: 7.4Assay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent