BDBM284884 5-iodo-7-[1-(oxan-4-yl)-1H-indazol-6- yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine::US10023576, Example 75

SMILES Nc1ncnn2c(cc(I)c12)-c1ccc2cnn(C3CCOCC3)c2c1

InChI Key InChIKey=SBNOIRJXGDXFNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284884   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM284884(5-iodo-7-[1-(oxan-4-yl)-1H-indazol-6- yl]pyrrolo[2...)
Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent