BDBM284994 N-[4-methyl-3-(2-methyl-1-oxoisoquinolin- 4-yl)phenyl]methanesulfonamide::US10023592, Example 39

SMILES Cc1ccc(NS(C)(=O)=O)cc1-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=RYGKANGIHXJREX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284994   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM284994(N-[4-methyl-3-(2-methyl-1-oxoisoquinolin- 4-yl)phe...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent