BDBM284996 N-[4-fluoro-3-[2-methyl-6-(1-methylpyrazol-4- yl)-1-oxoisoquinolin-4- yl]phenyl]methanesulfonamide::US10023592, Example 41

SMILES Cn1cc(cn1)-c1ccc2c(c1)c(cn(C)c2=O)-c1cc(NS(C)(=O)=O)ccc1F

InChI Key InChIKey=AEOXMKJVUSKLDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284996   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM284996(N-[4-fluoro-3-[2-methyl-6-(1-methylpyrazol-4- yl)-...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent