BDBM28500 (3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulfanyl]phenyl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15l

SMILES Fc1cccc(Sc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cc2Cl)c1

InChI Key InChIKey=RJZPDKUWHMCJNM-TZIWHRDSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28500   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28500((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulf...)
Affinity DataIC50:  800nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28500((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulf...)
Affinity DataIC50:  630nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed