BDBM285001 4-[2-(cyclopropylmethoxy)-5- methylsulfonylphenyl]-2-methyl-6-(1- methylpyrazol-4-yl)isoquinolin-1-one::BDBM485845::US10023592, Example 46
SMILES Cn1cc(cn1)-c1ccc2c(c1)c(cn(C)c2=O)-c1cc(ccc1OCC1CC1)S(C)(=O)=O
InChI Key InChIKey=CPMGVEUSBYQWDO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285001
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair