BDBM285283 5-[3-[(2,6-dimethylphenyl)methoxy]-5- methylsulfonylphenyl]-1,3- dimethylpyridin-2-one::BDBM486127::US10023592, Example 331

SMILES Cc1cccc(C)c1COc1cc(cc(c1)S(C)(=O)=O)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=IOKGUKBEUPWMBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285283   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285283(5-[3-[(2,6-dimethylphenyl)methoxy]-5- methylsulfon...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285283(5-[3-[(2,6-dimethylphenyl)methoxy]-5- methylsulfon...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent