BDBM285683 US10077273, Compound HK-13::US10934305, Compound HK-13
SMILES COc1cc(Cl)cc(c1)C1(C(C)C)c2c(C)n[nH]c2OC(N)=C1C#N
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285683
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 500nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 500nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair