BDBM286077 1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-indol-6-yl)-1H-pyrazole-4-carboxamide::US10081632, Compound 4::US10758530, Compound 4::US9771366, Compound 4

SMILES CN1CCN(Cc2c[nH]c3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1

InChI Key InChIKey=VSLDKPAIVWRXRV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286077   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286077(1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286077(1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286077(1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent