BDBM286084 (R)-1-benzyl-N-(4-methyl-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indol-7-yl)-1H-pyrazole-4-carboxamide::BDBM286088::US10081632, Compound 11::US10758530, Compound 11

SMILES C[C@@H]1CNC(=O)c2cc3ccc(NC(=O)c4cnn(Cc5ccccc5)c4)cc3n12

InChI Key InChIKey=FJRMMCYDWPNSIQ-LLVKDONJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 286084   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286084((R)-1-benzyl-N-(4-methyl-1-oxo-1,2,3,4-tetrahydrop...)
Affinity DataIC50:  1.38E+6nMAssay Description:The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286084((R)-1-benzyl-N-(4-methyl-1-oxo-1,2,3,4-tetrahydrop...)
Affinity DataIC50:  1.38E+3nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286084((R)-1-benzyl-N-(4-methyl-1-oxo-1,2,3,4-tetrahydrop...)
Affinity DataIC50:  1.38E+6nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286084((R)-1-benzyl-N-(4-methyl-1-oxo-1,2,3,4-tetrahydrop...)
Affinity DataIC50:  9.40E+4nMAssay Description:The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent