BDBM286090 (R)żN-(1-(2-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamide::BDBM342168::US10081632, Compound 17::US10758530, Compound 17

SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2N)c1

InChI Key InChIKey=RTMXBFRXLJUUNI-MRXNPFEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286090   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286090((R)żN-(1-(2-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)
Affinity DataIC50:  1.40E+4nMAssay Description:The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286090((R)żN-(1-(2-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)
Affinity DataIC50:  14nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286090((R)żN-(1-(2-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)
Affinity DataIC50:  1.40E+4nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent