BDBM28898 2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid::rhodanine derivative, 57

SMILES OC(=O)CN1C(=S)S\C(=C/c2csc3ccccc23)C1=O

InChI Key InChIKey=OUWYJOICAYBELE-WZUFQYTHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 28898   

TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50:  1.30E+4nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: >2.00E+5nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plates in which each reaction mixture contained SNAPtide, BoNT /A (List Biological...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50:  2.17E+4nMAssay Description:Inhibition of recombinant Bacillus cereus BC2 expressed in Escherichia coli BL21 (DE3) cells using FC4-FC5 as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: >1.00E+5nMAssay Description:This assay was performed as outlined in the Anaspec MMP assay kit. The fluorescence peptide cleavage assay was performed in a 96-well plate in which ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM28898(2-[(5Z)-5-(1-benzothiophen-3-ylmethylidene)-4-oxo-...)
Affinity DataIC50: >1.00E+5nMAssay Description:This assay was performed as outlined in the Anaspec MMP assay kit. The fluorescence peptide cleavage assay was performed in a 96-well plate in which ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed