BDBM2905 4,1-Benzoxazepinone analogue 2e::7-chloro-5-[(E)-2-cyclopropylethenyl]-5-(trifluoromethyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-2-one

SMILES FC(F)(F)C1(OCC(=O)Nc2ccc(Cl)cc12)\C=C\C1CC1

InChI Key InChIKey=RIFHBKAORDJJNW-AATRIKPKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2905   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2905(4,1-Benzoxazepinone analogue 2e | 7-chloro-5-[(E)-...)
Affinity DataIC50:  108nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed