BDBM291105 5-(2-fluoro- ethyloxy-d4)-1-(2- fluoro-4- (tetrahydro-2H- pyran-4-yl)phenyl) 3-(1-phenyl-1H- pyrazol-5- yl)pyridazin-4(1H) one::US9579407, Example 00164
SMILES [2H]C([2H])(F)C([2H])([2H])Oc1cn(nc(-c2ccnn2-c2ccccc2)c1=O)-c1ccc(cc1F)C1CCOCC1
InChI Key InChIKey=RPDUPLFOPDEGSF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 291105
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Takeda Pharmaceutical
US Patent
Takeda Pharmaceutical
US Patent
Affinity DataIC50: <10nMpH: 7.4 T: 2°CAssay Description:Human PDE1A, 3A, 4D2, 5A1, 7B, 8A1, 9A2, and 11A4 enzymes were purchased from BPS Bioscience. Human PDE6AB enzyme was purchased from Scottish Biomedi...More data for this Ligand-Target Pair