BDBM291138 US9580396, Example 5a
SMILES CN1C(=N)N[C@@]2(CCCc3ccc(NC(=O)c4cn5cc(ccc5n4)C#N)cc23)CS1(=O)=O
InChI Key InChIKey=LCBYLSGVNOSMHV-QFIPXVFZSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 291138
Affinity DataKi: 636nMpH: 5.0Assay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.13E+3nMpH: 5.0Assay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair