BDBM29136 CHEMBL92401::Euphozid::Iprazid::Iproniazid

SMILES CC(C)NNC(=O)c1ccncc1

InChI Key InChIKey=NYMGNSNKLVNMIA-UHFFFAOYSA-N

Data  3 KI  153 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 29136   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.61E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human MAOA by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of human MAOB by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BT1-TN-5B1-4 cells assessed as inhibition of production of hydrogen peroxide ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BT1-TN-5B1-4 cells assessed as inhibition of production of hydrogen peroxide ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.55E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.57E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29136(CHEMBL92401 | Euphozid | Iprazid | Iproniazid)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed