BDBM29142 substituted chalcone, 5i
SMILES COc1ccc(C(=O)\C=C\c2ccc(Cl)cc2)c(O)c1
InChI Key InChIKey=PSHLSUYKYJMBFH-RUDMXATFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 29142
Affinity DataIC50: 4.40nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair