BDBM291519 (E)-N-(3-(4-amino-6-(4-phenoxyphenoxy)pyrimidin-5-yl)phenyl)-4-(dimethylamino)but-2-enamide ::US10413562, Compound A248::US9580449, Example A248

SMILES CN(C)C\C=C\C(=O)Nc1cccc(c1)-c1c(N)ncnc1Oc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=UQJKGYDUTSFPQB-KPKJPENVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291519   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM291519((E)-N-(3-(4-amino-6-(4-phenoxyphenoxy)pyrimidin-5-...)
Affinity DataIC50: <100nMAssay Description:2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC-AHA-EEPL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent