BDBM292095 4-[4-(4-aminopiperidin-1-yl)-1-(4- cyclopropyl-3-fluorophenyl)-6- oxopyrimidin-2-yl]-2-fluorobenzonitrile::US10100046, Example 33::US9902719, Example 33

SMILES NC1CCN(CC1)c1cc(=O)n(-c2ccc(C3CC3)c(F)c2)c(n1)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=FLOKQIAPBONYCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292095   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM292095(4-[4-(4-aminopiperidin-1-yl)-1-(4- cyclopropyl-3-f...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM292095(4-[4-(4-aminopiperidin-1-yl)-1-(4- cyclopropyl-3-f...)
Affinity DataIC50: <100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent