BDBM293563 US10106527, Compound 273::US10544128, Compound 273::US10604514, Compound 76::US11548872, Compound 273::US20230286945, Compound 273::US9951048, Compound 273

SMILES Cn1cncc1-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCOCC3)cc2c1

InChI Key InChIKey=ZABAYWAGMFKGHJ-UHFFFAOYSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293563   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM293563(US10106527, Compound 273 | US10544128, Compound 27...)
Affinity DataEC50:  1.10nMT: 2°CAssay Description:Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1× Kinase buffer to final concentrations of 0.19 μg/mL, 30 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM293563(US10106527, Compound 273 | US10544128, Compound 27...)
Affinity DataEC50:  2.90E+3nMT: 2°CAssay Description:Briefly, recombinant GSK3β kinase, ATP and Ser/Thr peptide 09 are prepared in 1× Kinase buffer to final concentrations of 0.04 μg/mL, 46 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent