BDBM293602 US10106527, Compound 374::US10544128, Compound 374::US11548872, Compound 374::US20230286945, Compound 374::US9951048, Compound 374

SMILES CNc1ncc(s1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CC(C3)N(C)C)cc2c1

InChI Key InChIKey=YMLZMDBPLDQPLF-UHFFFAOYSA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293602   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM293602(US10106527, Compound 374 | US10544128, Compound 37...)
Affinity DataEC50:  5.46E+3nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM293602(US10106527, Compound 374 | US10544128, Compound 37...)
Affinity DataEC50:  3.80nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Divis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent