BDBM295697 Example 47 in WO2010147792::US10570125, Example 47::US11084810, Example 47 in WO2010147792::US11725004, Example 47 in WO2010147792

SMILES CN(C1CCN(CC1)S(C)(=O)=O)C(C)(C)C(=O)Nc1cc(no1)C(C)(C)CO

InChI Key InChIKey=LYKUIXANSLSAKB-UHFFFAOYSA-N

Data  1 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 295697   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  0.850nMAssay Description:CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  51.5nMAssay Description:CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  0.850nMAssay Description:CB2: CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37°...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataIC50:  3.10E+3nMAssay Description:CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  0.850nMAssay Description:CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  3.10E+3nMAssay Description:CHO cells expressing human CB1 R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  0.850nMAssay Description:CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295697(Example 47 in WO2010147792 | US10570125, Example 4...)
Affinity DataEC50:  3.10E+3nMAssay Description:CB1: CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37°...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent