BDBM295700 US10112934, Example 7::US11084810, Example 7::US11725004, Example 7

SMILES CN(CC1CCOCC1)C(C)(C)C(=O)Nc1nnc(s1)C(C)(C)C#N

InChI Key InChIKey=VVNNXSXQBQNJMJ-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 295700   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295700(US10112934, Example 7 | US11084810, Example 7 | US...)
Affinity DataEC50:  25nMAssay Description:CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295700(US10112934, Example 7 | US11084810, Example 7 | US...)
Affinity DataEC50:  2.00E+5nMAssay Description:CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295700(US10112934, Example 7 | US11084810, Example 7 | US...)
Affinity DataIC50: >2.00E+5nMAssay Description:CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295700(US10112934, Example 7 | US11084810, Example 7 | US...)
Affinity DataEC50: >2.00E+5nMAssay Description:CHO cells expressing human CB1 R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295700(US10112934, Example 7 | US11084810, Example 7 | US...)
Affinity DataEC50:  25nMAssay Description:CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM295700(US10112934, Example 7 | US11084810, Example 7 | US...)
Affinity DataEC50:  25nMAssay Description:CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent