BDBM296006 3-[(2R)-4-hydroxy-1-[3- methoxy-4-(1H-pyrazol- 4-yl)benzoyl]pyrrolidin- 2-yl]-N-(2-hydroxy-2- methylpropyl)benzamide::US10112939, Example 47
SMILES COc1cc(ccc1-c1cn[nH]c1)C(=O)N1CC(O)C[C@@H]1c1cccc(c1)C(=O)NCC(C)(C)O
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 296006
Affinity DataIC50: 7.29nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair