BDBM29714 Pyridoimidazolone, 5n
SMILES FC(F)(F)c1ccc(N2CCOCC2)c(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)cc2)c1
InChI Key InChIKey=UITKWEPMTYDTTM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 29714
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute of Cancer Research
The Institute of Cancer Research
Affinity DataIC50: 860nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair