BDBM297773 US10118929, Compound A1

SMILES OC(=O)CC(N1CCN(CCCCNc2nc3ccccc3[nH]2)C1=O)c1cccc(c1)C(F)(F)F

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 297773   

TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Scifluor Life Sciences

US Patent
LigandPNGBDBM297773(US10118929, Compound A1)
Affinity DataIC50:  376nMAssay Description:The optimized protocol was validated by employing reference compounds such as Cilengitide (+Vβ3/αVβ5−VN interaction) and CWHM12 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6/beta-8(Homo sapiens (Human))
Scifluor Life Sciences

US Patent
LigandPNGBDBM297773(US10118929, Compound A1)
Affinity DataIC50:  0.130nMAssay Description:The optimized protocol was validated by employing reference compounds such as Cilengitide (+Vβ3/αVβ5−VN interaction) and CWHM12 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-8(Homo sapiens (Human))
Scifluor Life Sciences

US Patent
LigandPNGBDBM297773(US10118929, Compound A1)
Affinity DataIC50:  50.4nMAssay Description:The optimized protocol was validated by employing reference compounds such as Cilengitide (+Vβ3/αVβ5−VN interaction) and CWHM12 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent