BDBM298278 7-((4- carboxybicyclo[2.2.2]octan- 1-yl)carbamoyl)-3-(5-chloro- 2-(1H-tetrazol-1-yl)phenyl)- 6,7-dihydro-5H- cyclopenta[b]pyridine=1- oxide::US10123995, Example 2

SMILES OC(=O)C12CCC(CC1)(CC2)NC(=O)C1CCc2cc(c[n+]([O-])c12)-c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=NCOMODHPSJZBSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298278   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM298278(7-((4- carboxybicyclo[2.2.2]octan- 1-yl)carbamoyl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent