BDBM298279 4-({[(7S)-3-(3-chloro-2,6- difluorophenyl)-1-oxido-6,7- dihydro-5H- cyclopenta[b]pyridin-b7- yl]carbonyl}amino)benzoic acid::US10123995, Example 3::US10123995, Example 4

SMILES OC(=O)c1ccc(NC(=O)C2CCc3cc(c[n+]([O-])c23)-c2c(F)ccc(Cl)c2F)cc1

InChI Key InChIKey=FPWOMQMRMSZCKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298279   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM298279(4-({[(7S)-3-(3-chloro-2,6- difluorophenyl)-1-oxido...)
Affinity DataIC50:  2.37E+3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM298279(4-({[(7S)-3-(3-chloro-2,6- difluorophenyl)-1-oxido...)
Affinity DataIC50:  2.92E+3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent