BDBM298338 US10123995, Example 16

SMILES OC(=O)c1ccc(NC(=O)[C@@]2(F)C[C@@H](F)c3cc(cnc23)-c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key InChIKey=JQFHMMXOQIRFDU-WZONZLPQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298338   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM298338(US10123995, Example 16)
Affinity DataIC50:  85.6nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent