BDBM298343 7-((4-carboxyphenyl)carbamoyl)-3-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)-7-(cyclopropylmethyl)-6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide (Example 21 and 22)::US10123995, Example 21::US10123995, Example 22
SMILES CC(C)(C)OC(=O)c1ccc(NC(=O)C2(CC3CC3)CCc3cc(c[n+]([O-])c23)-c2cc(Cl)ccc2-n2cnnn2)cc1
InChI Key InChIKey=GEXURDHGLNAAJU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 298343
Affinity DataIC50: 178nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Affinity DataIC50: >870nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair