BDBM299178 N-(2-(5-Methoxyisoindolin-2-yl)-6-methylpyrimidin-4-yl)-1H-indazol-5-amine::US10125144, Example 6::US11311541, Example 186
SMILES COc1ccc2CN(Cc2c1)c1nc(C)cc(Nc2ccc3[nH]ncc3c2)n1
InChI Key InChIKey=LORUKWDAVJYKND-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 299178
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair