BDBM300808 (3S)-3-[4-[[3-[4-(1,1-Dioxo-3,6- dihydro-2H-thiopyran-4-yl)-2- methyl- phenyl]benzo[b]thiophen-5- yl]methoxy]phenyl] hex-4-ynoic acid::US10131648, Compound 6::US10195178, Compound 6::US9790198, Compound 6

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccc(cc4C)C4=CCS(=O)(=O)CC4)c3c2)cc1

InChI Key InChIKey=APCRUVMVJQVQKD-SANMLTNESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300808   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300808((3S)-3-[4-[[3-[4-(1,1-Dioxo-3,6- dihydro-2H-thiopy...)
Affinity DataEC50:  15nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300808((3S)-3-[4-[[3-[4-(1,1-Dioxo-3,6- dihydro-2H-thiopy...)
Affinity DataEC50:  15nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300808((3S)-3-[4-[[3-[4-(1,1-Dioxo-3,6- dihydro-2H-thiopy...)
Affinity DataEC50:  15nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent