BDBM300814 (3S)-3-(4-((3-(4-(3-Hydroxy-3- methylbutoxy)-2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl) hex-4-ynoic acid::US10131648, Compound 12::US10195178, Compound 12::US9790198, Compound 12

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccc(OCCC(C)(C)O)cc4C)c3c2)cc1

InChI Key InChIKey=PMNDJSPIHMGDSU-VWLOTQADSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300814   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300814((3S)-3-(4-((3-(4-(3-Hydroxy-3- methylbutoxy)-2- me...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300814((3S)-3-(4-((3-(4-(3-Hydroxy-3- methylbutoxy)-2- me...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300814((3S)-3-(4-((3-(4-(3-Hydroxy-3- methylbutoxy)-2- me...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent