BDBM300822 (3S)-3-(4-((3-(2- Bromophenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl) hex-4-ynoic acid::US10131648, Compound 20::US10195178, Compound 20::US9790198, Compound 20

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccccc4Br)c3c2)cc1

InChI Key InChIKey=SSQUHTACGLVKPR-FQEVSTJZSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300822   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300822((3S)-3-(4-((3-(2- Bromophenyl)benzo[b]thiophen- 5-...)
Affinity DataEC50:  5nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300822((3S)-3-(4-((3-(2- Bromophenyl)benzo[b]thiophen- 5-...)
Affinity DataEC50:  5nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300822((3S)-3-(4-((3-(2- Bromophenyl)benzo[b]thiophen- 5-...)
Affinity DataEC50:  5nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent