BDBM300826 (3S)-3-(4-(((3-(2-Methyl-4-(3- (methylsulfonyl)propoxy)phenyl) benzo[b]thiophen-5- yl)oxy)methyl)phenyl) hex-4-ynoic acid::US10131648, Compound 24::US10195178, Compound 24::US9790198, Compound 24

SMILES CC#C[C@@H](CC(O)=O)c1ccc(COc2ccc3scc(-c4ccc(OCCCS(C)(=O)=O)cc4C)c3c2)cc1

InChI Key InChIKey=FCDKEILOONTNAC-VWLOTQADSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300826   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300826((3S)-3-(4-(((3-(2-Methyl-4-(3- (methylsulfonyl)pro...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300826((3S)-3-(4-(((3-(2-Methyl-4-(3- (methylsulfonyl)pro...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300826((3S)-3-(4-(((3-(2-Methyl-4-(3- (methylsulfonyl)pro...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent