BDBM300831 2-(1-(4-((3-(4-(1,1- Dioxidotetrahydro-2H- thiopyran-4-yl)-2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl)-3- oxocyclobutyl)acetic acid::US10131648, Compound 29::US10195178, Compound 29::US9790198, Compound 29

SMILES Cc1cc(ccc1-c1csc2ccc(COc3ccc(cc3)C3(CC(O)=O)CC(=O)C3)cc12)C1CCS(=O)(=O)CC1

InChI Key InChIKey=MMKHMYMCAHNSDD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300831   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300831(2-(1-(4-((3-(4-(1,1- Dioxidotetrahydro-2H- thiopyr...)
Affinity DataEC50:  34nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300831(2-(1-(4-((3-(4-(1,1- Dioxidotetrahydro-2H- thiopyr...)
Affinity DataEC50:  34nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300831(2-(1-(4-((3-(4-(1,1- Dioxidotetrahydro-2H- thiopyr...)
Affinity DataEC50:  34nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent