BDBM300837 2-((1r,3r)-3-Hydroxy-1-(4-((3- (4-(2-ethoxyethoxy)-2- methylphenyl) benzo[b]thiophen-5- yl)methoxy)phenyl)cyclobutyl) acetic acid::US10131648, Compound 35::US10195178, Compound 35::US9790198, Compound 35

SMILES CCOCCOc1ccc(-c2csc3ccc(COc4ccc(cc4)[C@@]4(CC(O)=O)C[C@H](O)C4)cc23)c(C)c1

InChI Key InChIKey=PMDQHXMPMWRWJX-LMGXKYGBSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300837   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300837(2-((1r,3r)-3-Hydroxy-1-(4-((3- (4-(2-ethoxyethoxy)...)
Affinity DataEC50:  26nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300837(2-((1r,3r)-3-Hydroxy-1-(4-((3- (4-(2-ethoxyethoxy)...)
Affinity DataEC50:  26nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300837(2-((1r,3r)-3-Hydroxy-1-(4-((3- (4-(2-ethoxyethoxy)...)
Affinity DataEC50:  26nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent