BDBM300841 2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methylpyridin-3- yl)benzo[b]thiophen-5- yl)methoxy)phenyl)cyclobutyl) acetic acid::US10131648, Compound 39::US10195178, Compound 39::US9790198, Compound 39

SMILES Cc1ncccc1-c1csc2ccc(COc3ccc(cc3)[C@@]3(CC(O)=O)C[C@H](O)C3)cc12

InChI Key InChIKey=WKTUCOMVKPREKH-DXKIZBQOSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300841   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300841(2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methylpyridin-3-...)
Affinity DataEC50:  46nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300841(2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methylpyridin-3-...)
Affinity DataEC50:  46nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300841(2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methylpyridin-3-...)
Affinity DataEC50:  46nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent