BDBM301929 US9598396, Compound 5a

SMILES C[C@](Cc1cccc(F)c1)(C#N)c1ccc2c3CCCCc3c(=O)[nH]c2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 301929   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301929(US9598396, Compound 5a)
Affinity DataIC50:  39.8nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301929(US9598396, Compound 5a)
Affinity DataIC50:  15.8nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent