BDBM301956 3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile::US9598401, Example 10

SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key InChIKey=YYSGFKYOICNQAC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 301956   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM301956(3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...)
Affinity DataKi:  1.30nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM301956(3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...)
Affinity DataKi:  200nMAssay Description:Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent