BDBM30359 BOC-piperidinyl glycine derivative, 34

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCN(CC1)C(=O)OC(C)(C)C)C(O)=O

InChI Key InChIKey=LFOGEPKUSWRLCL-JOCHJYFZSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 30359   

TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  0.398nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  6.60nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  33.7nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)
Affinity DataIC50:  1.37E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed