BDBM304688 (4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 49-4::US10144715, Compound 49-5

SMILES CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@@H](OC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O

InChI Key InChIKey=PYIUJPJVIHJOFC-LDQXTDLNSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 304688   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304688((4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl...)
Affinity DataKi:  7nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304688((4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl...)
Affinity DataKi:  44nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304688((4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl...)
Affinity DataKi:  70nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304688((4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl...)
Affinity DataKi:  421nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent