BDBM306620 (1S,8R)-N-[(4-carbamimidoyl- phenyl)methyl]-12-[(3- chlorophenyl)(methyl)amino]- 15-oxatetracyclo[6.6.1.02,7.09,14] pentadeca-2,4,6,9,11,13- hexaene-4-carboxamide::US10144746, Compound 263

SMILES CN(c1ccc2[C@@H]3O[C@H](c2c1)c1cc(ccc31)C(=O)NCc1ccc(cc1)C(N)=N)c1cccc(Cl)c1

InChI Key InChIKey=HISZJDSZTYNNBO-IZLXSDGUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306620   

TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

US Patent
LigandPNGBDBM306620((1S,8R)-N-[(4-carbamimidoyl- phenyl)methyl]-12-[(3...)
Affinity DataIC50:  1nMAssay Description:The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent