BDBM306642 (1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)methyl]- 12-(prop-1-en-2-yl)-15- oxatetracyclo[6.6.1.02,7.09,14] pentadeca-2,4,6,9,11,l3- hexaene-4-carboxamide::US10144746, Compound 285

SMILES CC(=C)c1ccc2[C@@H]3O[C@H](c2c1)c1cc(ccc31)C(=O)NCc1c(F)cc(cc1F)C(N)=N

InChI Key InChIKey=MKRQBUJZVKUPFP-BJKOFHAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306642   

TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

US Patent
LigandPNGBDBM306642((1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...)
Affinity DataIC50:  1nMAssay Description:The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent