BDBM306662 (1R,8S)-N-[(4-carbamimidoyl- 2-methylpheny])-methyl]-12- (2,4-difluorophenyl)-15- oxatetracyclo[6.6.1.02,7.09,14] pentadeca-2,4,6,9,11,13- hexaene-4-carboxamide::US10144746, Compound 306

SMILES Cc1cc(ccc1CNC(=O)c1ccc2[C@H]3O[C@@H](c2c1)c1cc(ccc31)-c1ccc(F)cc1F)C(N)=N

InChI Key InChIKey=WACSXFFOGDZEBB-WUFINQPMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306662   

TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

US Patent
LigandPNGBDBM306662((1R,8S)-N-[(4-carbamimidoyl- 2-methylpheny])-methy...)
Affinity DataIC50:  1nMAssay Description:The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent