BDBM306686 (1R,8S)-N-[(4-carbamimidoyl- 2,6-dimethyl-phenyl)methyl]- 12-cyclopropyl-15-oxatetracyclo [6.6.1.02,7.09,14]pentadeca- 2,4,6,9,11,13-hexaene-4- carboxamide::US10144746, Compound 331

SMILES Cc1cc(cc(C)c1CNC(=O)c1ccc2[C@H]3O[C@H](c4cc(ccc34)C3CC3)c2c1)C(N)=N

InChI Key InChIKey=SYSUACMAKJKASN-IZZNHLLZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306686   

TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

US Patent
LigandPNGBDBM306686((1R,8S)-N-[(4-carbamimidoyl- 2,6-dimethyl-phenyl)m...)
Affinity DataIC50:  1nMAssay Description:The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent