BDBM306704 (+-)-N-[(4- carbamimidoylphenyl) methyl]-6-fluoro-12-(4- fluorophenyl)-10-methyl-15- oxatetracyclo[6.6.1.02,7.09,14] pentadeca- 2(7),3,5,9(14),10,12- hexaene-4-carboxamide::US10144746, Compound 396

SMILES Cc1cc(cc2C3OC(c12)c1c3cc(cc1F)C(=O)NCc1ccc(cc1)C(N)=N)-c1ccc(F)cc1

InChI Key InChIKey=SJUIOQOVYSVNHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306704   

TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

US Patent
LigandPNGBDBM306704((+-)-N-[(4- carbamimidoylphenyl) methyl]-6-fluoro-...)
Affinity DataIC50:  5.01nMAssay Description:The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent