BDBM307528 (S)-1-(3-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylamino)-6-methylpyrimidin-5-yl)methyl)-3-methoxyphenoxy)propyl)pyrrolidine-2-carboxylic acid::US10150743, Example 9::US10562861, Ex. No. 9

SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(OCCCN2CCC[C@H]2C(O)=O)cc1OC

InChI Key InChIKey=RAOIMTPEPSLKEC-REWPJTCUSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307528   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM307528((S)-1-(3-(4-((2-amino-4-((S)-1-hydroxyhexan-3-ylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent