BDBM307725 (3R)-N-{5-chloro-4-[1-(2-fluorobenzyl)-1H-benzimidazol-6-yl]pyridin-2-yl}piperidine-3-carboxamide::US9650358, Example 21

SMILES Fc1ccccc1Cn1cnc2ccc(cc12)-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl

InChI Key InChIKey=KLRNGHMHUTUOQS-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307725   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM307725((3R)-N-{5-chloro-4-[1-(2-fluorobenzyl)-1H-benzimid...)
Affinity DataIC50:  17nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent